AIDS-related malignancies.

Relationship between current level of immunodeficiency and non-acquired immunodeficiency syndrome-defining malignancies.

BACKGROUND In the combined antiretroviral therapy (cART) era, non-acquired immunodeficiency syndrome (AIDS)-defining malignancies account for more morbidity and mortality in human immunodeficiency virus-infected patients than AIDS-defining malignancies. However, conflicting data have been reported on the relationship between immunodeficiency and the development of some non-AIDS-defining maligna...

AIDS-related malignancies: emerging challenges in the era of highly active antiretroviral therapy.

Human immunodeficiency virus (HIV)-infected patients are at increased risk of developing cancer, particularly in the later stages of acquired immune deficiency syndrome (AIDS). Despite the advent of highly active anti-retroviral therapy (HAART), malignancy in this population is a leading cause of morbidity and mortality. Kaposi's sarcoma (KS) and AIDS-related non-Hodgkin's lymphoma (ARL) are th...

Epidemiology of AIDS-Defi ning Malignancies

R. Yarchoan (ed.), Cancers in People with HIV and AIDS: Progress and Challenges, DOI 10.1007/978-1-4939-0859-2_2, © Springer Science+Business Media New York 2014 Abstract AIDS-defi ning malignancies are a subset of HIV-associated malignancies that include Kaposi sarcoma, some forms of non-Hodgkin lymphoma (NHL), and invasive cervical cancer (see also Chap. 3 ). Kaposi sarcoma along with Pneumoc...

Risk of cancers during interrupted antiretroviral therapy in the SMART study.

OBJECTIVE To compare rates of AIDS-defining and non-AIDS-defining malignancies between patients on a CD4 T-cell-guided antiretroviral therapy (ART) strategy and continuous ART. DESIGN A randomized clinical trial. METHODS Malignancy rates were compared between the drug conservation arm in which ART was stopped if the CD4 T-cell count exceeded 350 cells/microl and (re)started if it fell to le...

Genotypic distribution of HHV-8 in AIDS individuals without and with Kaposi sarcoma: Is genotype B associated with better prognosis of AIDS-KS?: Erratum